1. Dr Bhanu heads the HTA resource center for Uttarakhand at AIIMS Rishikesh.
Developed guidelines for the appropriate use of Transcatheter Aortic Valve Replacement (TAVR) versus Surgical Aortic Valve Replacement (SAVR).
Drafted a policy brief comparing the effectiveness of Cardiotocography (CTG) and Fetal Doppler.
Led the creation of the Hospital Preparedness Index (HOSPI) for COVID patients.
Conducted an in-depth evaluation of National Health Insurance programs. Published in Economic and Political weekly in Sept, 2024.
Published a paper in PloS One related to the COVID-19 pandemic exposed the challenges healthcare systems faced in balancing the provision of both COVID-19 and non-COVID-19 care, highlighting the need for more resilient and adaptable infrastructures.
2. BIRAC funded the development of a Smartphone-Based Rapid, Portable, Cardiac Biosensor Device Using Flexible Gel-Less Antibacterial Ag Nanorods Array.
Pioneered the development of cutting-edge dry electrodes for ECG monitoring.
Enhanced electrode performance to achieve accuracy and reliability comparable to conventional gold-standard electrodes.
Authored two research papers currently under revision.
3. ICMR funded The Yoga Care HF Trial to explore the effectiveness of yoga-based rehabilitation in heart failure patients. The trial is being conducted over a 2-year period, from 2023 to 2026.
Recognized as a top performer in a multi-centre yoga trial.
The trial integrates yoga with cardiac rehabilitation to offer an alternative therapy for heart failure patients.
Selected as one of the five leading centres out of 15 participants to conduct three specialized sub-studies.
Successfully completed a clinical trial with a one-year follow-up of 200 patients.
4. Non-invasive CAD diagnosis using coronary imaging.
A patent has been filled which focuses on plaque segmentation contributing to advancements in Coronary artery disease.
A research paper in the journal Pattern Recognition has already been accepted, addressing the PSIVUS/
Currently engaged in research on biomarkers, with a focus on identifying novel indicators for CAD, aiming to improve diagnostic and therapeutic outcomes.
Completed Projects
1. The National Program for Health Care of Elderly funded a study on Myocardial Systolic Function in Elderly Patients using 2D longitudinal speckle tracking. The project ran for 1.6 years, starting in July 2011.
Focused on assessing myocardial systolic function in elderly patients with normal left ventricular function
Utilized 2D longitudinal speckle tracking for a more detailed and accurate analysis of cardiac function
2. Awarded an International Fellowship as an Indian Council of Medical Research (ICMR) long-term fellow.
IVUS training at C5 IVUS Core lab at Cleveland clinic, USA
Established first Coronary Imaging lab in India
3. The Wellcome Trust-DBT funded a project on the Correlation of RNA profile with atherosclerotic plaque burden using Intravascular Ultrasound. The project ran from 2014 to 2017.
Established first Molecular Cardiology Lab in India
Provided new insights into plaque formation and cardiovascular risks
To understand the severity of atherosclerotic plaques using intravascular ultrasound.
4. The Wadhwani project: Coronary Imaging in CAD patients. The project ran from 2015 to 2017.
Investigated disease progression using coronary imaging.
5. The Uttarakhand Council of Science & Technology, Dehradun funded a 4-year project on the genetic polymorphism of ABCB1, CYP2C19, and P2Y12 genes.
The project investigated the genetic variations in these genes and their effect on the clinical efficacy of clopidogrel, a drug used to prevent blood clots.
Optimised a method to prepare PRP and perform LTA in the patients of CAD